Arteries Cleaning Technology 

 

What is it?

 

ACT - Thrombolysis is the breakdown of blood clots or atherosclerotic plaques (cholesterol deposits in arteries) by ultrasound together with thrombolytic drug. If a blood clot is forming in a blood vessel, it can lead to the blockage of it. Such a clot can be destroyed using ACT - Thrombolysis. 

 

ACT - Angioplasty is the procedure used to widen vessels narrowed by stenosis or occlusions. This widening occurs because of the ultrasound use. 

Our specialists suggested to use low-frequency high intensive ultrasound for the destruction of blood clots and atherosclerotic plaques together with thrombolytic drug. The first ACT - Thrombolysis was performed in 2001. Since that time about 30 patients have been operated. Thanks to this method of treatment all the patients have avoided the amputation. Now they can lead normal lives.

 

How it works?

 

When a blood clot arises in the artery, the blood flow can be significantly reduced or cut off completely. To save the patient’s limb doctors have to restore it as soon as possible. 

To this aim special shaped wire (ultrasound waveguide) is used, which is introduced into the artery after local anesthesia. When the waveguide reaches the place where the thrombus is located, an ultrasound is put on the blood clot and the artery walls. 

Under ultrasound influence the artery is widened, the blood clot breaks down and the blood flow is restored. Small fractions of the thrombus are sucked out of the body with a special pump. 

A self-expanding nitinol stent (metal mesh tube) is placed in the blood vessel, which hinders artery narrowing and new blood clots forming. 

Selective insertion of plasminogen activator - streptokinase in low quantities into the artery in conjunction with intravascular induction of high intensive ultrasound increases efficiency of the occlusion recanalization through activation of fibrinolysis and reduces risk of complications.

 

Why exactly ACT Trombolysis/Angioplasty use?

  • Patient does not need general anesthesia

  • Ultrasound disinfects vessel walls and facilitates access to the affected area

  • Short hospitalization (2-3 days)

  • Perforation of blood vessels and their injury is avoided due to the layerwise destruction of the blood clot

  • Years after the surgery the vessels are still clean

  • The Permeability of the arteries increases to 90 %

  • Direct success over 85%

  • General risk of complication below 5%

  • Frequency of re-occlusion in earlier periods below 10%

  • Increase of vessel elasticity

  • Increase of vessel permeability

 

Angiographic indications for the procedure
  1. Segmental stenosis or occlusion of common and external iliac arteries less than 10 cm in length with minimal pathological changes in peripheral vessels.

  2. Segmental stenosis or occlusion of the superficial femoral artery less than 10 cm in length with minimal pathological changes in peripheral blood vessels.

  3. Segmental stenosis or occlusion of the deep femoral artery less than 5 cm with minimal pathological changes in peripheral blood vessels.

  4. Segmental stenosis or occlusion of the popliteal artery and the shank artery less than 5 cm in length with minimal pathological changes in peripheral vessels.

  5. Segmental stenosis or occlusion of autovenous shunts.

 

Angiographic contraindications for the procedure

  1. Stenosis or occlusion of the iliac and femoral arteries, with a length of more than 10 cm, and pronounced changes in the peripheral channel.

  2. Stenosis or occlusion of the femoral artery, combined with the occlusion of the common iliac artery of the same limb, and pronounced changes in the peripheral channel.

  3. Stenosis or occlusion of the deep femoral artery, popliteal artery and shank arteries more than 5 cm in lenght, and pronounced changes in the peripheral channel.

  4. Stenosis and occlusion of arteries with a diameter of less than 2.5 mm.

  5. Severe or extensive calcification of lower limb arteries.

 

Before the procedure

 

The following tests are conducted before the procedure is performed: 

  • Physical and general clinical examination

  • Angiography of the arteries of lower limbs

  • Ultrasonic examination of lower limb arteries

  • Rheography of lower limb arteries

  • MRI of lower imb arteries